2023 ~ 生醫轉譯研究中心 核酸先導設施 專案經理
2020 ~ 生醫轉譯研究中心 博士後研究 (核酸先導設施建置)
2018 ~ 向榮生醫科技股份有限公司 轉譯研究部經理/協理
2017 ~ 元培醫事科技大學 兼任助理教授
2016 ~ 聯亞藥業股份有限公司 生物技術部 副理
2012 ~ 日本九州大學 訪問學者
2006 ~ 台北醫學大學 藥學院 博士
2003 ~ 台北醫學大學 生藥學研究所 碩士

藥理學, 動物疾病模式建立, 活性篩選平台建立, 臨床前動物實驗規劃, 專案管理, 核酸製程開發及品質分析。

101-104台北醫學大學優秀博士後獎
2016年聯亞集團傑出貢獻獎

1. Ruei Min Lu, Hsiang En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan Hong Chen, Ming Hsiang Hong, Yin Shiou Lin, Ching Hang Liu, Shih Han Ko, Christian Angelo P. Concio, Yi Jen Su, Yi Han Chang, Wen Shan Li and Han Chung Wu. Current landscape of mRNA technologies and delivery systems for new modality therapeutics. Journal of Biomedical Science, 2024, 31:89.
2. Yuh-Hwa Liu, Yin-Shiou Lin(equal first)#, Yi-Yan Sie , Ching-Chiung Wang, Chi-I Chang, Wen-Chi Hou. Vitisin B, a resveratrol tetramer from Vitis thunbergii var. taiwaniana, ameliorates impaired glucose regulations in nicotinamide streptozotocin-induced type 2 diabetic mice. Journal of Traditional and Complementary Medicine 2023, 13 479-488.
3. I Jung Lee, Cheng Pu Sun, Ping Yi Wu, Yu Hua Lan, I Hsuan Wang, Wen Chun Liu, Joyce Pei Yi Yuan, Yu Wei Chang, Sheng Che Tseng, Szu I Tsung, Yu Chi Chou, Monika Kumari, Yin Shiou Lin, Hui Feng Chen, Tsung Yen Chen, Chih Chao Lin, Chi Wen Chiu, Chung Hsuan Hsieh, Cheng Ying Chuang, Chao Min Cheng, Hsiu Ting Lin, Wan Yu Chen, Fu Fei Hsu, Ming Hsiang Hong, Chun Che Liao, Chih Shin Chang, Jian Jong Liang, Hsiu Hua Ma, Ming Tsai Chiang, Hsin Ni Liao, Hui Ying Ko, Liang Yu Chen, Yi An Ko, Pei Yu Yu, Tzu Jing Yang, Po Cheng Chiang, Shang Te Hsu, Yi Ling Lin, Chong Chou Lee, Han Chung Wu and Mi Hua Tao. A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants. Journal of Biomedical Science.2022, 29:49.
4. Cheng-Pu Sun, Jia-Tsrong Jan, I-Hsuan Wang, Hsiu-Hua Ma, Hui-Ying Ko, Ping-Yi Wu Tzu-Jiun Kuo, Hsin-Ni Liao Yu-Hua Lan, Zong-Lin Sie, Yen-Hui Chen, Yi-An Ko, Chun-Che Liao, Liang-Yu ChenI I-Jung Lee, Szu-I Tsung, Yun-Ju Lai, Ming-Tsai Chiang, Jian-Jong Liang, Wen-Chun Liu, Jing-Rong Wang, Joyce Pei-Yi Yuan, Yin-Shiou Lin, Yi-Ching Tsai, Shie-Liang Hsieh, Chia-Wei Li, Han-Chung Wu, Tai-Ming Ko, Yi-Ling Lin, Mi-Hua Tao. Rapid generation of mouse models for emerging infectious disease with the case of severe COVID-19. PLOS Pathogens. 2021,17(8):e1009758.
5. Chia En Lien, Yi Jiun Lin, Charles Chen, Wei Cheng Lian, Tsun Yung Kuo, John D. Campbell, Paula Traquina, Meei Yun Lin, Luke Tzu Chi Liu, Ya Shan Chuang, Hui Ying Ko, Chun Che Liao, Yen Hui Chen, Jia Tsrong Jan, Hsiu Hua Ma, Cheng Pu Sun, Yin Shiou Lin, Ping Yi Wu, Yu Chiuan Wang, Mi Hua Tao, & Yi Ling Lin. CpG adjuvanted stable prefusion SARS CoV 2 spike protein protected hamsters from SARS CoV 2 challenge. Scientific Reports. 2021, 11:8761.
6. Yuh-Hwa Liu, Yin-Shiou Lin, Yu-Wei Huang, Sheng-Uei Fang, Shyr-Yi Lin, and Wen-Chi Hou*.Protective effects of minor components of curcuminoidson hydrogen peroxide-treated human HaCaTkeratinocytes. Journal of Agricultural and Food Chemistry2016, 64:3598-608.
7. Yin-Shiou Lin, Chuan-Hsiao Han, Shyr-Yi Lin, and Wen-Chi Hou*.Synthesized peptides from yam dioscorinhydrolysis in silicoexhibitdipeptidylpeptidase-IV inhibitory activities and oral glucosetolerance improvements in normal mice.Journal of Agricultural and Food Chemistry 2016, 64, 6451−6458.
8. Yin-Shiou Lin, Chiy-Rong Chen, Wei-Hau Wu, Chi Luan Wen, Chi-I Chang*, and Wen-Chi Hou*. Anti-α-glucosidase and anti-dipeptidylpeptidase-IV activities of extracts and purified compounds from Vitisthunbergii var. taiwaniana. Journal of Agricultural and Food Chemistry2015, 63:6393-401.
9. Yuh-Hwa Liu, Yin-Shiou Lin(equal first)#, Kuan-Ling Lin, Yeh-Lin Lu, Chao-Hsiang Chen,Mei-Yin Chien, Huey-Fang Shang, Shyr-Yi Lin* and Wen-Chi Hou*.Effects of hot-water extracts from Ganodermalucidum residues and solid-statefermentation residues on prebiotic and immune-stimulatory activities in vitro andthe powdered residues used as broiler feed additives in vivo . Botanical Studies2015, 56:17.(doi:10.1186/s40529-015-0097-3)
10. Shen-Liang Shih, Yin-ShiouLin(equal first)#, Shyr-Yi Lin*, and Wen-Chi Hou*. Effects of yam dioscorin interventions on improvements of themetabolic syndrome in high-fat diet-induced obese rats. Botanical Studies2015, 56:4.(doi:10.1186/s40529-015-0084-8)
11. Yin-Shiou Lin, Wen-Chung Wu, Shyr-Yi Lin, and Wen-Chi Hou*.Glycine hydroxamate inhibits tyrosinase activity and melanin contents throughdownregulatingcAMP/PKA signaling pathways . Amino Acids2015, 47:617–625.
12. Chuan-Hsiao Han#,Yin-Shiou Lin(equal first)#,Tai-Lin Lee,Hong-Jen Liang*and Wen-Chi Hou*. Asn-Trp dipeptides improve the oxidative stress andlearning dysfunctions in D-galactose-inducedBALB/c mice. Food&Function2014, 5, 2228–2236.
13. Yin-Shiou Lin,Yeh-Lin Lu, Guei-Jane Wang, Hong-Jen Liang*,and Wen-Chi Hou*.Vasorelaxing and antihypertensive activities of synthesized peptides derived fromcomputer-aided simulation of pepsin hydrolysis of yam dioscorin. Botanical Studies2014, 55, 49.(doi:10.1186/s40529-014-0049-3)
14. Chuan-Hsiao Han,Yuh-Feng Lin, Yin-Shiou Lin, Tai-Lin Lee, Wei-Jan Huang, Shyr-Yi Lin*,and Wen-Chi Hou*.Effects of yam tuber protein, dioscorin, on attenuating oxidative statusand learning dysfunction in D-galactose-induced BALB/c mice. Food and Chemical Toxicology 2014, 65, 356–363.
15. Chuan-Hsiao Han#, Yin-Shiou Lin (equal first)#, Shyr-Yi Lin*, and Wen-Chi Hou*. Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorinhydrolysis and its analogue, Gln-Trp. Food Chemistry2014, 147, 195–202.
16. Yuh-Hwa Liu,Yin-Shiou Lin, Tai-Lin Lee, Wen-Chi Hou*. Semicarbazide-sensitive amine oxidase inhibitory and hydroxyl raical scavenging activities of aspartic acid β-hydroxamate and glutamic acid γ-monohydroxamate. Botanical Studies 2012, 53, 301-306.
17. Yin-Shiou Lin, Yeh-Lin LU, Guei-Jane Wang, Lih-Geeng Chen, Chi-Luan Wen*, Wen-Chi Hou*. The ethanolic extracts and isolated compounds from small-leaf grape (Vitis thunbergii var. taiwaniana) with antihypertensive activities. Journal of Agricultural and Food Chemistry 2012, 60, 7425-7441.
18. Yin-Shiou Lin, Mao-Te Chuang, Chao-Hsiang Chen, Mei-Yin Chien, Wen-Chi Hou*. Nicotinic acid hydroxamate downregulated the melanin synthesis and tyrosinase activity through activating the MEK/ERK and AKT/GSK3β signaling pathways. Journal of Agricultural and Food Chemistry 2012, 60, 4859-4864.
19. Chao-Hsiang Chen, Yin-Shiou Lin, Mei-Yin Chen, Wen-Chi Hou*, and Miao-Lin Hu*. Antioxidant and antihypertensive activities of acteoside and its analogs. Botanical Studies 2012, 53, 421-429.
20. Yin-Shiou Lin, Sheng-Hsuan Chen, Wei-Jan Huang, Chao-Hsiang Chen, Mei-Yin Chien, Shyi-Yi Lin, Wen-Chi Hou*. Effects of nicotinic acid derivatives on tyrosinase inhibitory and antioxidant activities. Food Chemistry 2011, 132, 2074-2080.
21. Chuan-Hsiao Han, Ju-Chi Liu, Kwan-Han Chen,Yin-Shiou Lin, Ching-Tan Chen, Chien-Teng Fan, Der-Zen Liu, Wen-Chi Hou*. Antihypertensive activities of processed garlic on spontaneously hypertensive rats and hypertensive humans. Botanical Studies 2011, 52, 277-283.
22. Chun-Yao Huang, Chi-Luan Wen, Yeh-Lin Lu, Yin-Shiou Lin, Lih-Geeng Chen, Wen-Chi Hou*. Antihypertensive activities of extracts from tissue cultures of Vitis thunbergii var. taiwaniana. Botanical Studies 2010, 51, 317-324.