Core Facilities for Translational Medicine

To promote the development of domestic biotechnology, the National Biotechnology Research Park has brought together several sets of advanced instrument systems and hired research consultants and professional technicians to establish the Core Facilities for Translational Medicine (CFTM). The purpose is to support resident scientific research teams and biotech companies to carry out biomedical innovation research. It serves as a bridge between basic biomedical research and the development of biotechnology for academic research institutions, biotechnology, and pharmaceuticals. We hope to improve biomedical and drug research capabilities and promote the development of domestic biotechnology. The core facilities contain five key technology platforms, respectively: (1) Cell Sorting and Analyzing Core Facility (2) CTC Capture and Single Cell Analysis Core Facility (3) High-Dimensional Advanced Imaging Core Facility (4) Digital Pathology Core Facility (5) Automatic Living Cell Assay Core Facility. We support the following eight main research directions:

1. Precision medicine in cancer treatment: Understanding cancer subtype cells via gene mapping or follow-up on cancer treatment prognosis via extracting patient CTC (Circulating tumor cell) for cell culture platform and BD Rhapsody™ Single Cell Analysis System.
2. Cancer immunology research: Deciphering the interaction of cancer and immune cells, evaluation of cancer-immune treatment reaction.
3. Cancer and tissue fibrosis matrix research: Establishment of 2D and 3D cell structural images to conduct tissue matrix macro and micro perspective analysis, using tissuegnostics scanning and SP8-DIVE Deep In Vivo Explorer Multiphoton confocal microscopy techniques.
4. Cancer cell drug reaction research: Understanding cancer cell drug reaction analysis via flow cytometers, automatic image analysis, cell culture, and multifunction optical analysis systems.
5. Research on neurodegenerative, metabolic, cardiovascular disease, and precision medicine: Understanding tissue regeneration prototypes and mechanism with combinative techniques of SP8-DIVE Deep In Vivo Explorer Multiphoton confocal microscope, LSM 880 with Airyscan confocal microscope, Gate STED microscopy technology.
6. Transplant immunology research: Evaluation of post-transplant surgery immunology reaction with high-end flow cytometric analysis, and tissue section images from automated high-throughput scanning imaging systems.
7. Stem cell research: Equipped with a high-class hypoxia workstation for cell culturing platform and supported by flow cytometer technology, the facility is ideal for various embryotic and somatic stem cell culturing and pluripotent induced stem cell experiments.
8. Research on personalized disease models: Understanding personalized disease models via simulating humanized mouse models for drug discovery. Function supported by the five key technology platforms of core facilities.

Contact us

Website: 

https://cftm.biotrec.sinica.edu.tw/
https://cftm.nbrp.sinica.edu.tw/

E-mail: cftm@gate.sinica.edu.tw
TEL: 02-7750-5554/7750-5556