陳建璋博士
中央研究院生醫轉譯研究中心 主任
中央研究院學術及儀器事務處 處長
中央研究院生物醫學科學研究所 研究員
🕿 (02)7750-5859
🖂 chienchangchen@as.edu.tw
🌐 Website
Dr. Chien-Chang Chen works in the field of physiology, with his research focusing on the mechanisms underlying the development of persistent chronic pain using optogenetics, chemogenetics, in vivo imaging, gene targeting, electrophysiological, pharmacological and behavioral approaches in wild type and genetically modified mice. Dr. Chen’s early studies at IBMS focused on understanding the role of T-type Ca2+ channels in brain and cardiovascular system, especially related to human diseases such as cardiac ischemia- reperfusion injury, cardiac hypertrophy, platelet function and pain sensation. For the past ten years, however, Dr. Chen’s laboratory has actively investigated the role of the anterior nucleus of paraventricular thalamus (PVA) in chronic pain and the formation of hyperalgesia priming. Dr. Chen’s studies show that PVA is involved in the development and maintenance of chronic in several rodent models. Dr. Chen also investigates the underlying mechanism for the transition from acute pain to chronic pain. Dr. Chen received his Ph.D. in Physiology and Biophysics from University of Illinois at Urbana-Champaign and post-doctoral training in ion channel and mouse genetics at Howard Hughes Medical Institute at University of Iowa.
Dr. Chen accepted a faculty position as an Assistant Research Fellow at the Institute of Biomedical Sciences at Academia Sinica in 2005, earning promotion to Associate Research Fellow in 2011 and to Research Fellow/Professor in 2018. Dr. Chen served as the Director of the Department of International Affairs from 2019-2020. He is currently the Director of the Department of Academic Affairs and Instrument Services at Academia Sinica.
Education
| 1985-1989 | B.S. Zoology, National Taiwan University, Taipei, Taiwan. |
| 1989-1991 | M.S. Zoology, National Taiwan University, Taipei, Taiwan. |
| 1991-1993 | M.S. Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign. |
| 1993-1998 | Ph.D. Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign. |
Professional Experiences
| 2025-date | Director, Biomedical Translation Research Center, Academia Sinica. |
| 2020-date | Director, Department of Academic Affairs and Instrument Service, Academia Sinica. |
| 2019-2020 | Director, Department of International Affairs, Academia Sinica. |
| 2018-date | Research Fellow, Institute of Biomedical Sciences, Academia Sinica. |
| 2011-2018 | Associate Research Fellow, Institute of Biomedical Sciences, Academia Sinica. |
| 2005-2011 | Assistant Research Fellow, Institute of Biomedical Sciences, Academia Sinica. |
| 2003-2005 | Assistant Research Scientist, Department of Physiology and Biophysics at University of Iowa. |
| 1998-2003 | Postdoctoral research fellow, Howard Hughes Medical Institute at University of Iowa. |
